Homoeopathic Perspectives on the Pathophysiology and Treatment of Skin Aging
DOI:
https://doi.org/10.48165/ahr.2025.10.4.5Keywords:
Skin rigidity, Autonomic innervation, cumulative photo ageing, wrinkles, vesselsAbstract
The skin is one of the largest and most important organs in the body and comprises approximately 16% of the human body weight. It has a number of physiological functions that are essential to maintaining homeostasis, protection and social interaction. Protection, thermoregulation, sensation, water storage, absorption, expression, synthesis of vitamin D. The skin is the main interface between the individual and the environment. It therefore has essential physiological functions which allow the individual to live safely, even under changing external conditions which might pose potential threats. The skin has 3 layers—the epidermis, dermis, and hypodermis, which have different anatomical structures and functions. The epidermis is derived from ectodermal tissue. The dermis and hypodermis are derived from mesodermal tissue. Nerves of the skin include both somatic and autonomic nerves. The somatic sensory system transmits pain (nociception), temperature, light touch, discriminative touch, vibration, pressure, and proprioception sensations to the central nervous system. Autonomic innervation controls vasculature tone, hair root pilomotor stimulation, and sweating. The free nerve endings extend into the epidermis and are responsible for sensing pain, heat, and cold.
References
McKnight, G., Shah, J., & Hargest, R. Physiology of the skin. Surgery (Oxford). 2022;40(1):8–12.
Yousef, H., Alhajj, M., & Sharma, S. Anatomy, Skin (Integument), Epidermis.
National Center for Biotechnology Information. Anatomy, skin (integument), epidermis. Available at:
https://www.ncbi.nlm.nih.gov/books/NBK470464/
Farage, M. A., Miller, K. W., Elsner, P., & Maibach, H. I. Intrinsic and extrinsic factors in skin ageing: A review. International Journal of Cosmetic Science. 2008;30(2):87–95.
Chaudhary, M., Khan, A., & Gupta, M. Skin ageing: Pathophysiology and current market treatment approaches. Current Aging Science. 2019;13(1):22–30. doi:10.2174/1567205016666190809161115
NGLORA. What is intrinsic ageing? [Internet]. 2025 Apr 22. Available at:
https://www.skinceuticals.co.uk/en_GB/what-is-intrinsic-ageing.html
NGLORA. What is extrinsic ageing? [Internet]. 2025 Apr 22. Available at:
https://www.skinceuticals.co.uk/en_GB/extrinsic-ageing-what-is-it.html
Zhang, S., & Duan, E. Fighting against skin aging: The way from bench to bedside. Cell Transplantation. 2018;27(5):729–738. doi:10.1177/0963689717725755
Press Information Bureau, Government of India. Healing touch of Homoeopathy for skin diseases [Internet]. Available at:
https://www.pib.gov.in/PressReleaseIframePage.aspx?PRID=1663640
Boericke, W. Pocket Manual of Homeopathic Materia Medica & Repertory. New Delhi, India: B. Jain Publishers; 2007.
Boger, C. M. Boenninghausen’s Characteristics Materia Medica & Repertory with Word Index. New Delhi: B. Jain Publishers; 2002.
Kent, J. T. Repertory of the Homoeopathic Materia Medica – Médi-T [Internet]. Available at:

