An Overview of Amperometric Biosensors for Clinical and Medicinal Drug Monitoring
Keywords:
Amperometric, Biosensors, Enzyme Electrodes, Electro Analysis, GlucoseAbstract
Endogenous substances and therapeutic medicines may be determined quickly and easily in clinical samples thanks to the combination of enzymes and electrode transducers. New advances in electrochemical biosensor operation, downsizing, and microfabrication open up new prospects for biological and pharmacological investigation. This study looks at the current state of amperometric enzyme electrodes (AEE) in biomedicine which focus on recent developments and tasks. Continuous drug monitoring is a viable alternative to existing therapeutic drug monitoring (TDM) methods, with the potential to significantly change our knowledge of pharmacokinetic variability and enhance personalized treatment. This study focuses on current advancements in bio-sensing technologies that enable real-time drug surveillance. We mainly work on biosensors based on aptamers, as well as wearable and implantable devices. The methods used in the construction of biosensors are highlighted.
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