Ayurvedic Management Of Duodenal Ulcer: A Clinical Case Study
DOI:
https://doi.org/10.48165/pimrj.2025.2.2.12Keywords:
Duodenal ulcer, Ayurveda, Gastritis, Hyperacidity, Amlapitta, Amashaya, Fatty liver, Yakrit RogaAbstract
Duodenal ulcer, a type of peptic ulcer disease, is characterized by an open sore in the lining of the duodenum—the first part of the small intestine—primarily caused by excessive gastric acid secretion, Helicobacter pylori infection, or prolonged use of NSAIDs, leading to symptoms such as epigastric pain, acidity, and indigestion. This case study evaluates the integrative management of a 31-year-old male patient diagnosed with a duodenal ulcer, who presented to Jeena Sikho Lifecare Limited Hospital, Ambala, Haryana, India with chief complaints of gastritis and hyperacidity persisting for over five years. The patient had a history of alcohol consumption and exhibited elevated bilirubin levels upon initial evaluation. A holistic Ayurvedic treatment protocol was initiated, which included classical Ayurvedic formulations for their cooling and demulcent effects. A strict Pitta shamana diet was also advised. After Ayurvedic intervention, the patient reported significant symptomatic relief, including the resolution of gastritis and hyperacidity. Objective findings supported clinical improvement, with total bilirubin decreasing from 1.58 mg/dL to 0.98 mg/dL and corresponding improvements in direct and conjugated bilirubin levels, indicating better hepatic function. USG findings also demonstrated abdominal improvement. This case highlights the potential of Ayurvedic therapies in managing duodenal ulcers effectively. While results are promising, further large-scale and controlled studies are necessary to validate these outcomes and standardize treatment protocols.
References
Sung JJ, Kuipers EJ, El-Serag HB. Systematic review: The global incidence and prevalence of peptic ulcer disease. Alimentary Pharmacology & Therapeutics. 2009 May 1;29(9):938–946. doi:10.1111/j.1365-2036.2009.03960.x. PMID: 19220208.
Chey WD, Wong BC; Practice Parameters Committee of the American College of Gastroenterology. American College of Gastroenterology guideline on the management of Helicobacter pylori infection. American Journal of Gastroenterology. 2007 Aug;102(8):1808–1825. doi:10.1111/j.1572-0241.2007.01393.x. PMID: 17608775.
Laine L, Jensen DM. Management of patients with ulcer bleeding. American Journal of Gastroenterology. 2012 Mar;107(3):345–360; quiz 361. doi:10.1038/ajg.2011.480. PMID: 22310222.
Lanas A, Chan FKL. Peptic ulcer disease. The Lancet. 2017 Aug 5;390(10094):613–624. doi:10.1016/S0140-6736(16)32404-7. PMID: 28242110.
Pillai NR, Seshadri C, Santhakumari G. Anti-ulcerogenic activity of Ayurvedic preparation Taramanduram: A preliminary study. Indian Journal of Pharmacology. 1979;11(2):93–99.
Desai P, Saroj UR, Garg GK, Bhawana, Neeraj. Gastroprotective effect of Samudradya Churna with special reference to Parinama Shula: A classical review. Ayushdhara. 2023 Sep 9;10(Suppl 4):79–82. Available from: https://ayushdhara.in/index.php/ayushdhara/article/view/1259
Roy AJ, Maut C, Gogoi HK, Ahmed SI, Kashyap A. Herbal drugs used in the treatment of peptic ulcer: A review. Current Drug Discovery Technologies. 2023;20(3):e121222211869. doi:10.2174/1570163820666221212142221. PMID: 36515023.
Gupta H, Shakya MK, Sharma GK. Evaluation of anti-ulcer activity of a polyherbal preparation in ulcerogenic Wistar rats. Research Journal of Pharmacy and Technology. 2022;15(8):3471–3474. doi:10.52711/0974-360X.2022.00581.
Kumar M, Ghosh A, Yadav K, Dileep K, Singh A, Maurya S. Kamadugha Rasa: An effective Ayurvedic formulation for peptic ulcer—A review. International Journal of Ayurvedic Medicine. 2014;3:24–32.
Jain AS, et al. An anatomical study of Pittadhara Kala: A review article. International Ayurvedic Medical Journal. 2020. Available from: http://www.iamj.in/posts/images/upload/3387_3390.pdf
Kumar S, Bharti P, Kumari R, Singh VB. Annadrava Shoola and Parinama Shoola versus peptic ulcer disease: An Ayurvedic and modern review. Ayushdhara. 2022;9(4):79–82. doi:10.47070/ayushdhara.v10i4.945.
Prajapati ND. A handbook of medicinal plants: A complete source book. Jodhpur: Agrobios India; 2003.
Chowdary BR. 360 Degree Postural Therapy. New Delhi: Diamond Pocket Books; 2021.
Baragi P, Baragi U. A critical review of Amlapitta (gastritis). Journal of Ayurveda and Integrated Medical Sciences. 2017;2(1). doi:10.21760/jaims.v2i1.7507.
Sharma RK, Dash B. Charaka Samhita. Vol. 4: Chikitsa Sthana. Varanasi: Chowkhamba Sanskrit Series Office; 2010.

