Doppler Ultrasonographic Study on Haemodynamic Alterations in Medically Terminated Canine Pregnancies
DOI:
https://doi.org/10.48165/ijvsbt.21.4.03Keywords:
uteroplacental artery, umbilical artery, Doppler, Resistive index, progesteroneAbstract
This study evaluated maternal and fetal haemodynamic changes in medically terminated canine pregnancies using Doppler ultrasonography. Twelve pregnant bitches (35-40 days gestation) were divided into a Group I (control group, n=6) and Group II (treatment group n=6). A combination protocol of cloprostenol (1 µg/kg SC every 48 h) and cabergoline (5 µg/kg PO daily) was used to induce abortion for bitches in group II. Parameters assessed included biparietal diameter (BPD), combined thickness of uterus and placenta (CTUP), fetal heart rate (FHR), progesterone levels, and Doppler parameters (PSV, EDV, RI, PI, S/D ratio) in the uteroplacental artery (UPA), umbilical artery (Uma) and fetal aorta (FA). All group II bitches aborted within 3-5 days, with progesterone dropping below 1 ng/mL by day 5. Significant haemodynamic disruptions were observed post-treatment, including increased UPA resistance (RI >0.61, EDV <15 cm/s) and diminished Uma diastolic flow, signaling placental insufficiency. No structural differences in BPD or CTUP were noted. These findings underscore Doppler’s role in high-risk pregnancy management and abortion monitoring in canines.
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References
Alonge, S., et al. (2016). Feto-maternal heart rate ratio in pregnant bitches. Reproduction in Domestic Animals, 51(5), 688–692.
Beccaglia, M., & Luvoni, G.C. (2012). Prediction of parturition in dogs and cats. Reproduction in Domestic Animals, 47, 194–196.
Bigliardi, E., et al. (2004). Cystic hyperplasia-pyometra complex via ultrasonography. Reproduction in Domestic Animals, 39(3), 136–140.
Blanco, P.G., et al. (2009). Uterine artery resistance index in canine pregnancy. Reproduction in Domestic Animals, 44, 164–166.
Blanco, P.G., et al. (2011). Doppler of maternal and fetal blood flow in abnormal pregnancy. Animal Reproduction Science, 126(1–2), 130–135.
Corrada, Y., et al. (2006). Oral cabergoline and cloprostenol for pregnancy termination. JAAHA, 42(5), 366–370.
Di Salvo, P., et al. (2006). Doppler of maternal/fetal vessels in normal gestation. Research in Veterinary Science, 81(3), 382–388.
England, G.C.W., et al. (1990). Canine pregnancy via B-mode ultrasound. Journal of Small Animal Practice, 31(7), 324–329.
England, G., et al. (2003). Ultrasound of reproductive tract. In: Recent Advances in Small Animal Reproduction, IVIS.
Feliciano, M.A.R., et al. (2014). Triplex Doppler for prenatal canine diagnostics. Acta Scientiae Veterinariae, 42(1), 1–5.
Fieni, F., et al. (1997). PGF2α protocol for pregnancy termination. Journal of Reproduction and Fertility. Supplement, 51, 245–250.
Gaikwad, S.M., et al. (2017). Uterus and placenta measurements in canines. Journal of Bombay Veterinary College, 24(1), 83–87.
Gaikwad, S.M. (2018). Foeto-maternal Doppler in canine gestation. Ph.D. Thesis, MAFSU, Nagpur.
Gaikwad, S.M., et al. (2020). Doppler of maternal vessels in canine abortion. Irish Veterinary Journal, 73, 1–9.
Kustritz, M.V.R. (2009). Clinical Canine and Feline Reproduction. Wiley.
Luvoni, G.C., & Beccaglia, M. (2006). Parturition prediction in canine pregnancy. Reproduction in Domestic Animals, 41(1), 27–32.
Maldonado, A.L.L., et al. (2012). Gestational age by placental thickness. Veterinary Medicine International, 2012, 850867.
Miranda, S.A., & Domingues, S.F.S. (2010). Triplex Doppler in dogs. Theriogenology, 74(4), 608–617.
Nautrup, C.P. (1998). Doppler of fetal arteries in normal gestation. Reproduction, 112(2), 301–314.
Nyland, T.G., & Mattoon, J.S. (2002). Small Animal Diagnostic Ultrasound. Elsevier.
Onclin, K., & Verstegen, J.P. (1999). PGF2α analogues for pregnancy termination. Veterinary Record, 144(15), 416–419.
Parmar, B.M., et al. (2020). Termination in mismated bitches. Indian J Vet Sci Biotech, 16(2–4), 89–91.
Reddy, K.R.C., et al. (2010). Therapeutic efficacy for pregnancy termination. Indian Journal of Animal Reproduction, 31(2), 19–22.
Simon, S., et al. (2022). Doppler in canine pregnancy management. Indian Journal of Animal Research, 56(7), 811–821.
Thangamani, A., et al. (2018). Review of pregnancy termination in dogs. IJSET, 7(2), 486–491.
Troisi, A., et al. (2023). Ovarian tumour findings in bitches. Theriogenology, 210, 227–233.
Umamageswari, J., et al. (2018). Doppler indices in bitch gestation. Indian Journal of Animal Reproduction, 39(1), 41–43.
Valocky, I., et al. (1997). Ultrasonographic biometry for gestational age. Folia Veterinaria, 41(3/4), 123–127.
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