Pathological study of rabies in canine brain
DOI:
https://doi.org/10.48165/ijvsbt.21.5.036Keywords:
Canine, rabies, brain, gross, histopathologyAbstract
A pathological study on canine brain tissue suspected with rabies was carried out on necropsy cases received at the Department of Veterinary Pathology, Madras Veterinary College Chennai, during April to September, 2019. Twenty-seven dogs presented for necropsy were considered for the study. The clinical history, age, breed and sex wise distribution were recorded. Gross changes if any was observed and samples of brain tissues were collected for histopathological studies. Brain impression smears were stained with William’s modification of Van Gieson’s stain and observed for presence of Negri bodies. Out of 27 dogs examined eight cases showed presence of Negri bodies. No significant gross changes were observable except for congestion, oedema and hemorrhages. Histopathological studies revealed subdural hemorrhages, marked gliosis, perivascular lymphocytic cuffing, neutrophilic vacuolation and presence of intracytoplasmic eosinophilic inclusions in neurons of cerebral grey matter.
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