Characterization of Luteal Response to PGF2α Treatment During Mid-luteal Phase in Graded Murrah Buffaloes
DOI:
https://doi.org/10.48165/ijar.2025.46.01.5Keywords:
Corpus luteum, Buffalo, Luteolysis, Progesterone, PGF2αAbstract
The present study was conducted with the objective to evaluate the functional and structural regression of corpus luteum following administration of PGF2 α during mid-luteal phase of estrous cycle in graded Murrah buffaloes. Healthy, plu riparous lactating and cyclic graded Murrah buffaloes (n=7; 6-8 years) were administered with PGF2 alpha (Cloprostenol sodium, 500µg) intramuscularly during mid-luteal phase of estrous cycle and recorded luteolysis (functional, structural regression) and corresponding follicular growth periodically from time of administration (0, 6, 12, 24, 48hr and 72 hr). Results showed that the significant decrease in size of CL at 24, 48hr and 72 hr, while progesterone concentration reached to its basal level (<1 ng/ml) at 12 hr of PGF2bα administration. Subsequently, ovulation of the existing follicle was also observed from 48 to 72 hr after administration of PGF2α in buffaloes. Therefore, the present study is documented that the exogenous administration of PGF2α causes the structural regression and reduced concentration of P4 which enhances the existing follicle to become functional. Hence, exogenous administration of prostaglandin will be the most effective way of synchronization of estrus in cyclic animals thus enhancing the reproductive potential in buffaloes.References
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